In silico drug target screening for NF
Question:
Use variant, gene expression, or drug screening data from different sources and apply already-published or new methods to predict drug targets that could be helpful in treating manifestations of NF1, NF2, or schwannomatosis.
Dataset(s):
Publicly accessible drug screen data on tumors, processed variant or gene expression data from different sources (e.g. NF Data Portal, cBioPortal, GENIE, Pediatric Brain Tumor Atlas), any other datasets that you can find.
Example Solutions:
All teams must produce a ranked list of drugs for NF1-related tumors, NF2-related tumors, and/or schwannomatosis-related tumors. Organizers will aggregate the ranked lists and will publish this list openly (e.g., F1000) for the NF research community to mine.